She is credited with the innovation of the "Angelator", which is later recreated/replaced with a newer version, the "Angelatron".
She is the only member of the Medico-Legal Lab staff who does not hold an advanced degree.
Her middle name is meant to be an allusion to her father's guitar "Miss Pearly Gates".
While initially on good terms, they grew closer throughout season one.
At the beginning of season two, Hodgins became obviously interested in her, and pursued her more openly.
In one episode, the character Jack Hodgins was quoted as saying Angela "was the heart of the operation." Angela contemplates leaving the Jeffersonian at one point, under the assumption that her work does not contribute to cases in a meaningful way.
She was also unsure of her ability to handle the graphic violence she was exposed to regularly at the lab. Goodman, the director of the Jeffersonian, spoke of the vital importance of her work in adding an element of humanity to the victims, returning their identity.